Original paper
Cyclodextrin polymers decorated with RGD peptide as delivery systems for targeted anti-cancer chemotherapy
Abstract
Polymeric cyclodextrin-based nanoparticles are currently undergoing clinical trials as nanotherapeutics. Using a non-covalent approach, we decorated two cross-linked cyclodextrin polymers of different molecular weights with an RGD peptide derivative to construct a novel carrier for the targeted delivery of doxorubicin. RGD is the binding sequence for the integrin receptor family that is highly expressed in tumour tissues. The assembled...
Paper Details
Title
Cyclodextrin polymers decorated with RGD peptide as delivery systems for targeted anti-cancer chemotherapy
Published Date
Dec 17, 2018
Journal
Volume
37
Issue
4
Pages
771 - 778
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Notes
History