CNS phenotype in X linked Charcot- Marie-Tooth disease

We read with interest the study by Koutsis et al reporting an increased prevalence of multiple sclerosis (MS) in their cohort of patients with X linked Charcot-Marie-Tooth disease (CMTX1).1 CMTX1 is a neurological condition with significant disability. The suggestion that CMTX1 may be a risk factor for developing MS will be of significant concern for these patients. We have a large cohort of patients with CMTX1 (n=133) in our centre. We...