Review paper
The Balancing Act between Cancer Immunity and Autoimmunity in Response to Immunotherapy
Abstract
The explosion in novel cancer immunotherapies has resulted in extraordinary clinical successes in the treatment of multiple cancers. Checkpoint inhibitors (CPIs) that target negative regulatory molecules have become standard of care. However, with the growing use of CPIs, alone or in combination with chemotherapy, targeted therapies, or other immune modulators, a significant increase in immune-related adverse events (irAEs) has emerged. The...
Paper Details
Title
The Balancing Act between Cancer Immunity and Autoimmunity in Response to Immunotherapy
Published Date
Dec 1, 2018
Journal
Volume
6
Issue
12
Pages
1445 - 1452
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