Match!

Investigation of graded-level soybean meal diets in red drum (Sciaenops ocellatus) using NMR-based metabolomics analysis

Published on Mar 1, 2019in Comparative Biochemistry and Physiology Part D: Genomics and Proteomics
· DOI :10.1016/j.cbd.2018.11.009
Fabio Casu2
Estimated H-index: 2
(NIST: National Institute of Standards and Technology),
Aaron M. Watson2
Estimated H-index: 2
(South Carolina Department of Natural Resources)
+ 6 AuthorsDaniel W. Bearden21
Estimated H-index: 21
(NIST: National Institute of Standards and Technology)
Abstract
Abstract We investigated changes in the metabolome in juvenile red drum (Sciaenops ocellatus) induced by increasing amounts of soybean meal (0% to 60%) in extruded, fishmeal-free diets using a nuclear magnetic resonance spectroscopy (NMR)-based metabolomics approach in a 12-week feeding trial. All of the diets were composed of ≈40% total crude protein, ≈11% total crude lipid and were energetically balanced. A fishmeal-containing, commercial extruded diet was used as a control diet throughout the trial. Each week, liver, muscle, intestine and plasma samples were collected and analyzed by NMR to provide a “snapshot” of the metabolome at different time points. Results indicate significant time-dependence of the metabolic profiles in various tissues with stable metabolomic profiles forming after about 9-weeks on the experimental diets. We identify a previously unexploited biomarker of potential dietary stress (N‑formimino‑ l ‑glutamate (FIGLU)) in the fish that may prove to be useful for optimization of alternative diet formulations.
  • References (47)
  • Citations (3)
References47
Newest
#1Andrea C. Alfaro (AUT: Auckland University of Technology)H-Index: 20
#2Tim Young (AUT: Auckland University of Technology)H-Index: 9
#1William Cheung (IARC: International Agency for Research on Cancer)H-Index: 10
#2Pekka Keski-Rahkonen (IARC: International Agency for Research on Cancer)H-Index: 6
Last.Augustin Scalbert (IARC: International Agency for Research on Cancer)H-Index: 42
view all 30 authors...
#1A.-C. Hansen (NIN: National Institute of Nutrition, Hyderabad)H-Index: 9
#2Rune Waagbø (NIN: National Institute of Nutrition, Hyderabad)H-Index: 41
Last.Gro Ingunn Hemre (NIN: National Institute of Nutrition, Hyderabad)H-Index: 25
view all 3 authors...
#1Rani Abro (SLU: Swedish University of Agricultural Sciences)H-Index: 2
#2Ali A. Moazzami (SLU: Swedish University of Agricultural Sciences)H-Index: 16
Last.Torbjörn Lundh (SLU: Swedish University of Agricultural Sciences)H-Index: 18
view all 4 authors...
#1Tracey B. Schock (NIST: National Institute of Standards and Technology)H-Index: 7
#2Jessica Duke (NIST: National Institute of Standards and Technology)H-Index: 1
Last.Daniel W. Bearden (NIST: National Institute of Standards and Technology)H-Index: 21
view all 7 authors...
#1David S. Wishart (IARC: International Agency for Research on Cancer)H-Index: 84
#2Timothy Jewison (IARC: International Agency for Research on Cancer)H-Index: 8
Last.Augustin Scalbert (IARC: International Agency for Research on Cancer)H-Index: 56
view all 23 authors...
Cited By3
View next paperMetabolomics Analysis of Effects of Commercial Soy-based Protein Products in Red Drum (Sciaenops ocellatus)