Changes in Preoperative Endoscopic and Percutaneous Bile Drainage in Patients with Periampullary Cancer Undergoing Pancreaticoduodenectomy in Ontario: Effect on Clinical Practice of a Randomized Trial

In 2010, a multicentre randomized controlled trial reported increased postoperative complications in pancreaticoduodenectomy (pde) patients undergoing preoperative biliary decompression (pbd). We evaluated the effect of that publication on rates of pbd at the population level.This retrospective observational cohort study identified patients undergoing pde for malignancy, 2005-2013, linking them with administrative health care databases covering...