Body Composition and Cardiorespiratory Fitness Between Metabolically Healthy Versus Metabolically Unhealthy Obese Black and White Adolescents.
Abstract Purpose We compared body composition and cardiorespiratory fitness (CRF) between metabolically healthy overweight/obese (MHO) versus metabolically unhealthy overweight/obese (MUO) adolescents in 189 black and white adolescents (BMI ≥ 85th percentile, 12–18 years of age). Methods Participants were defined as MHO or MUO if their insulin-stimulated glucose disposal, measured by a 3-hour hyperinsulinemic-euglycemic clamp, was in the upper quartile or in the lower three quartiles. Total fat was measured by dual-energy X-ray absorptiometry, and visceral adiposity and liver fat were measured by magnetic resonance imaging and proton magnetic resonance spectroscopy, respectively. CRF was measured by a graded maximal treadmill test. Results Black MHO adolescents had lower (p Conclusions Independent of race, the MHO phenotype is characterized by high CRF, lower waist circumference and visceral fat, and lower rates of dysglycemia in youth.