Original paper
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy
Abstract
Outcomes of anticancer therapy vary dramatically among patients due to diverse genetic and molecular backgrounds, highlighting extensive intertumoral heterogeneity. The fundamental tenet of precision oncology defines molecular characterization of tumors to guide optimal patient-tailored therapy. Towards this goal, we have established a compilation of pharmacological landscapes of 462 patient-derived tumor cells (PDCs) across 14 cancer types,...
Paper Details
Title
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy
Published Date
Sep 27, 2018
Journal
Volume
50
Issue
10
Pages
1399 - 1411
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Notes
History