Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model

Background Fanconi anemia is an inherited bone marrow failure disorder associated with a high incidence of leukemia and solid tumors. Currently, no interventions to prevent or delay the formation of solid tumors are available. Procedure Two of the most important hallmarks of Fanconi anemia are inflammation and oxidative stress. In this study, we administrated the antioxidant atorvastatin and the anti‐inflammatory drug celecoxib to cohorts of...