Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer

Joaquín Cubiella; Marc Clos-Garcia; Cristina Alonso; Ibon Martínez-Arranz; Miriam Pérez-Cormenzana; Ziortza Barrenetxea; J. Berganza; Isabel Rodríguez-Llopis; Mauro D'Amato; Luis Bujanda; Juan M. Falcón-Pérez

doi:https://doi.org/10.3390/cancers10090300

doi.org/10.3390/cancers10090300

Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer

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..., Juan M. Falcón-Pérez

52

Cancers5.20

Volume: 10, Issue: 9, Pages: 300 - 300

Published: Sep 1, 2018

Abstract

Low invasive tests with high sensitivity for colorectal cancer and advanced precancerous lesions will increase adherence rates, and improve clinical outcomes. We have performed an ultra-performance liquid chromatography/time-of-flight mass spectrometry (UPLC-(TOF) MS)-based metabolomics study to identify faecal biomarkers for the detection of patients with advanced neoplasia. A cohort of 80 patients with advanced neoplasia (40 advanced adenomas...

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Paper Details

Title

Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer

DOI

doi.org/10.3390/cancers10090300

Published Date

Sep 1, 2018

Journal

Cancers

Volume

10

Issue

9

Pages

300 - 300

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