Genome and transcriptome profiling of relapsed and metastatic osteosarcoma.
Volume: 36, Issue: 15_suppl, Pages: 11522 - 11522
Published: May 20, 2018
Abstract
11522 Background: Osteosarcoma (OS) is characterized by genomic complexity and significant genetic heterogeneity. However, it is unknown whether relapse and metastatic samples incur additional insults to genomic integrity. To examine this, we conducted in-depth genomic profiling in a cohort of 48 pediatric and adult patients with high-grade OS including 42 patients with relapsed/metastatic disease. Methods: Whole-genome sequencing, RNA...
Paper Details
Title
Genome and transcriptome profiling of relapsed and metastatic osteosarcoma.
Published Date
May 20, 2018
Journal
Volume
36
Issue
15_suppl
Pages
11522 - 11522
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