Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts

Background & AimsMost patients with esophageal adenocarcinoma (EAC) present with de novo tumors. Although this could be due to inadequate screening strategies, the precise reason for this observation is not clear. We compared survival of patients with prevalent EAC with and without synchronous Barrett esophagus (BE) with intestinal metaplasia (IM) at the time of EAC diagnosis.MethodsClinical data were studied using Cox proportional hazards...