PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity
Abstract
Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 European-descent individuals identifies 44 PR interval loci (34 novel). Examination of these loci reveals known and previously not-yet-reported biological processes involved in cardiac atrial electrical activity. Genes in...
Paper Details
Title
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity
Published Date
Jul 25, 2018
Journal
Volume
9
Issue
1
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