Follow-up infarct volume as a mediator of endovascular treatment effect on functional outcome in ischaemic stroke

The putative mechanism for the favourable effect of endovascular treatment (EVT) on functional outcome after acute ischaemic stroke is preventing follow-up infarct volume (FIV) progression. We aimed to assess to what extent difference in FIV explains the effect of EVT on functional outcome in a randomised trial of EVT versus no EVT (MR CLEAN).FIV was assessed on non-contrast CT scan 5-7 days after stroke. Functional outcome was the score on the...