Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience
Abstract
Recently, we described a machine learning approach for classification of central nervous system tumors based on the analysis of genome-wide DNA methylation patterns [6]. Here, we report on DNA methylation-based central nervous system (CNS) tumor diagnostics conducted in our institution between the years 2015 and 2018. In this period, more than 1000 tumors from the neurosurgical departments in Heidelberg and Mannheim and more than 1000 tumors...
Paper Details
Title
Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience
Published Date
Jul 2, 2018
Journal
Volume
136
Issue
2
Pages
181 - 210
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