Review paper
The multifaceted role of glutathione S-transferases in cancer
Abstract
Glutathione S-transferases (GSTs) are phase II detoxifying enzymes involved in the maintenance of cell integrity, oxidative stress and protection against DNA damage by catalyzing the conjugation of glutathione to a wide variety of electrophilic substrates. Though enzymes of the glutathione synthesis and salvage pathways have been well characterized in the past, there is still a lack of comprehensive understanding of their independent and...
Paper Details
Title
The multifaceted role of glutathione S-transferases in cancer
Published Date
Oct 1, 2018
Journal
Volume
433
Pages
33 - 42
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