Review paper
Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease
Abstract
The global epidemic of obesity has been accompanied by a rising burden of non-alcoholic fatty liver disease (NAFLD), with manifestations ranging from simple steatosis to non-alcoholic steatohepatitis, potentially developing into hepatocellular carcinoma. Although much attention has focused on NAFLD, its pathogenesis remains largely obscure. The hallmark of NAFLD is the hepatic accumulation of lipids, which subsequently leads to cellular stress...
Paper Details
Title
Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease
Published Date
Oct 1, 2018
Journal
Volume
69
Issue
4
Pages
927 - 947
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Notes
History