Review paper

How the phagocyte NADPH oxidase regulates innate immunity

Volume: 125, Pages: 44 - 52
Published: Sep 1, 2018
Abstract
The phagocyte NADPH oxidase is a multi subunit protein complex that generates reactive oxygen species at cell membranes and within phagosomes. It is essential for host defence as evidenced by the severe immunodeficiency syndrome caused by a loss of one of the subunits. This is known as chronic granulomatous disease (CGD). However, the phagocyte NADPH oxidase also has a key role to play in regulating immunity and it is notable that chronic...
Paper Details
Title
How the phagocyte NADPH oxidase regulates innate immunity
Published Date
Sep 1, 2018
Volume
125
Pages
44 - 52
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