Review paper
Leveraging GWAS for complex traits to detect signatures of natural selection in humans
Abstract
Natural selection can shape the genetic architecture of complex traits. In human populations, signals of positive selection at genetic loci have been detected through a variety of genome-wide scanning approaches without the knowledge of how genes affect traits or fitness. In the past decade, genome-wide association studies (GWAS) have provided unprecedented insights into the genetic basis of quantitative variation in complex traits. Summary...
Paper Details
Title
Leveraging GWAS for complex traits to detect signatures of natural selection in humans
Published Date
Dec 1, 2018
Volume
53
Pages
9 - 14
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