Original paper
Regulation of innate and adaptive antitumor immunity by IAP antagonists
Abstract
Inhibition of the T-cell co-inhibitory checkpoint receptors or their ligands CTLA-4, PD-1 and PD-L1 using monoclonal antibodies has proven to be highly effective against many cancers. Yet many cancers remain resistant to checkpoint blockade, and durable remissions occur in only a minority of patients. Novel approaches to enhancing antitumor responses are thus necessary in order to expand the reach of these treatments. The inhibitor of apoptosis...
Paper Details
Title
Regulation of innate and adaptive antitumor immunity by IAP antagonists
Published Date
Jul 1, 2018
Journal
Volume
10
Issue
9
Pages
787 - 796
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Notes
History