Original paper
Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment
Volume: 545, Issue: 1-2, Pages: 84 - 92
Published: Jul 1, 2018
Abstract
Glioblastoma multiforme is the most lethal type of brain tumor and the established therapy only extends patients survival to approximately one year. Its first-line treatment is based on of chemotherapy with the alkylating agent temozolomide (TMZ). As many other chemotherapeutic drugs, TMZ presents several limitations as high toxicity and low bioavailability. The delivery of TMZ using poly(lactic-co-glycolic acid) nanoparticles is proposed in...
Paper Details
Title
Receptor-mediated PLGA nanoparticles for glioblastoma multiforme treatment
Published Date
Jul 1, 2018
Volume
545
Issue
1-2
Pages
84 - 92
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Notes
History