A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
Abstract
The extent to which heterogeneity within mesenchymal stem cell (MSC) populations is related to function is not understood. Using the archetypal MSC in vitro surface marker, CD90/Thy1, here we show that 30% of the MSCs in the continuously growing mouse incisor express CD90/Thy1 and these cells give rise to 30% of the differentiated cell progeny during postnatal development. In adulthood, when growth rate homeostasis is established, the CD90/Thy1+...
Paper Details
Title
A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors
Published Date
Jan 25, 2018
Journal
Volume
9
Issue
1
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