Original paper
Prominent microglial activation in cortical white matter is selectively associated with cortical atrophy in primary progressive aphasia
Volume: 45, Issue: 3, Pages: 216 - 229
Published: May 17, 2018
Abstract
Aims Primary progressive aphasia ( PPA ) is a clinical syndrome characterized by selective language impairments associated with focal cortical atrophy favouring the language dominant hemisphere. PPA is associated with Alzheimer's disease ( AD ), frontotemporal lobar degeneration ( FTLD ) and significant accumulation of activated microglia. Activated microglia can initiate an inflammatory cascade that may contribute to neurodegeneration, but...
Paper Details
Title
Prominent microglial activation in cortical white matter is selectively associated with cortical atrophy in primary progressive aphasia
Published Date
May 17, 2018
Volume
45
Issue
3
Pages
216 - 229
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Notes
History