Association Study of Astrocyte-Derived Protein S100B Gene Polymorphisms with Major Depressive Disorder in Chinese People

Astroglial-derived protein S100B is known to play important roles in axonal growth, neural plasticity, and energy regulation. Disturbance of these neurodevelopmental processes is proposed as one possible etiology for mood disorder. Therefore, we performed a genetic analysis of S100B in patients with major depressive disorder (MDD).The polymorphisms of S100B were determined by polymerase chain reaction-restriction fragment length polymorphism in...