Eleven loci with new reproducible genetic associations with allergic disease risk

BackgroundA recent genome-wide association study (GWAS) identified 99 loci that contain genetic risk variants shared between asthma, hay fever, and eczema. Many more risk loci shared between these common allergic diseases remain to be discovered, which could point to new therapeutic opportunities.ObjectiveWe sought to identify novel risk loci shared between asthma, hay fever, and eczema by applying a gene-based test of association to results...