Follow‐up of a randomised phase II study of chemotherapy alone or in combination with mogamulizumab in newly diagnosed aggressive adult T‐cell leukaemia‐lymphoma: impact on allogeneic haematopoietic stem cell transplantation

Adult T cell leukaemia-lymphoma (ATL) is an aggressive peripheral T-cell lymphoma associated with human T-lymphotropic virus type 1. Four clinical subtypes of ATL have been identified: acute, lymphoma, chronic (favourable and unfavourable) and smouldering (Shimoyama, 1991). Systemic chemotherapy is usually administered to patients with acute, lymphoma, or unfavourable chronic (aggressive) ATL, who have a particularly poor prognosis (Ishitsuka &...