Original paper
A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity
Abstract
Cytoplasmic dynein is the major minus-end-directed microtubule-based motor in cells. Dynein processivity and cargo selectivity depend on cargo-specific effectors that, while generally unrelated, share the ability to interact with dynein and dynactin to form processive dynein-dynactin-effector complexes. How this is achieved is poorly understood. Here, we identify a conserved region of the dynein Light Intermediate Chain 1 (LIC1) that mediates...
Paper Details
Title
A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity
Published Date
Mar 7, 2018
Journal
Volume
9
Issue
1
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Notes
History