Review paper
Systematic evaluation of common lubricants for optimal use in tablet formulation
Abstract
As an essential formulation component for large-scale tablet manufacturing, the lubricant preserves tooling by reducing die-wall friction. Unfortunately, lubrication also often results in adverse effects on tablet characteristics, such as prolonged disintegration, slowed dissolution, and reduced mechanical strength. Therefore, the choice of lubricant and its optimal concentration in a tablet formulation is a critical decision in tablet...
Paper Details
Title
Systematic evaluation of common lubricants for optimal use in tablet formulation
Published Date
May 1, 2018
Volume
117
Pages
118 - 127
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