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Review paper

Personalized vaccines for cancer immunotherapy

Science44.70
Volume: 359, Issue: 6382, Pages: 1355 - 1360
Published: Mar 22, 2018
Abstract
Cancer is characterized by an accumulation of genetic alterations. Somatic mutations can generate cancer-specific neoepitopes that are recognized by autologous T cells as foreign and constitute ideal cancer vaccine targets. Every tumor has its own unique composition of mutations, with only a small fraction shared between patients. Technological advances in genomics, data science, and cancer immunotherapy now enable the rapid mapping of the...
Paper Details
Title
Personalized vaccines for cancer immunotherapy
Published Date
Mar 22, 2018
Journal
Volume
359
Issue
6382
Pages
1355 - 1360
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