Identification and Determination of Minimum Inhibitory Concentrations of Plant Extracts having Antimicrobial Activity as Potential Alternative Therapeutics to Treat Aeromonas hydrophila Infections

Published on Jan 1, 2018
Grace Ramena1
Estimated H-index: 1
Yathish Ramena1
Estimated H-index: 1
Nitin Challa1
Estimated H-index: 1
Aeromonas hydrophila causes infections in wide range of organisms including humans. It causes serious and life threatening lethal infections in humans. Motile aeromonas septicemia causes huge economic loss to fish farmers. Antibiotic use and abuse is a huge problem that is environmentally lethal, leading to antibiotic resistance and difficulty in treating bacterial infections. There is always a need to find new and safe alternatives to antibiotics to deal with bacterial infections. In this study we have evaluated 11 herb and spice extracts for their antimicrobial activity against Aeromonas hydrophila and compared their activity with commercially available antibiotic to treat this disease. We found that clove and cinnamon methanol extracts had significantly higher antibacterial effect against A. hydrophila when compared to oxytetracycline and other extracts. Both the extracts have higher activity at the lowest concentration tested (5 mg) and can potentially serve as alternative therapeutics to A. hydrophila infections in humans as well as fish.
  • References (30)
  • Citations (1)
📖 Papers frequently viewed together
2 Citations
4 Authors (Damiano F, ..., Glieca F)
78% of Scinapse members use related papers. After signing in, all features are FREE.
#1Jaromír LachmanH-Index: 26
#2D. ProněkH-Index: 1
Last. K. FaitováH-Index: 1
view all 6 authors...
Polyphenolic antioxidant compounds were studied in three onion varieties (red - cv. Karmen, yellow - cv. Vsetana and white - cv. Ala) regarding their total content and qualitative composition of flavonoid complex. The effects of temperature and storage period during onion storage were also studied. The total content of polyphenols was estimated spectrophotometrically with Folin-Ciocalteau's phenolic reagent and individual flavonoid components by HPLC method using Waters TM chromatograph on Watre...
64 CitationsSource
#1Aysegul Mutlu‐Ingok (ITU: Istanbul Technical University)H-Index: 1
#2Funda Karbancioglu-Guler (ITU: Istanbul Technical University)H-Index: 6
Natural antimicrobials as well as essential oils (EOs) have gained interest to inhibit pathogenic microorganisms and to control food borne diseases. Campylobacter spp. are one of the most common causative agents of gastroenteritis. In this study, cardamom, cumin, and dill weed EOs were evaluated for their antibacterial activities against Campylobacter jejuni and Campylobacter coli by using agar-well diffusion and broth microdilution methods, along with the mechanisms of antimicrobial action. Che...
12 CitationsSource
#1K.K. ChahalH-Index: 4
#2MonikaH-Index: 2
Last. R KaurH-Index: 1
view all 5 authors...
6 Citations
The clinical effectiveness of most of the marketed antimicrobials is found to be threatened by the rapid emergence of multidrug resistant pathogens which increase the need to find alternatives. Hundred years ago, essential oils have been known for their biologic activities in the folkloric medicine in many countries. The objective of our study was to investigate the antibacterial activity of some essential oils against different microorganisms and to study the possible effects between the tested...
5 CitationsSource
#1Mohsen Hamidpour (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 6
#2Rafie HamidpourH-Index: 6
Last. Mina ShahlariH-Index: 5
view all 4 authors...
For a long time, sage (Salvia) species have been used in traditional medicine for the relief of pain, protecting the body against oxidative stress, free radical damages, angiogenesis, inflammation, bacterial and virus infection, etc., Several studies suggest that sage species can be considered for drug development because of their reported pharmacology and therapeutic activities in many countries of Asia and Middle East, especially China and India. These studies suggest that Salvia species, in a...
60 CitationsSource
Clove (Syzygium aromaticum) is one of the most valuable spices that has been used for centuries as food preservative and for many medicinal purposes. Clove is native of Indonesia but nowadays is cultured in several parts of the world including Brazil in the state of Bahia. This plant represents one of the richest source of phenolic compounds such as eugenol, eugenol acetate and gallic acid and posses great potential for pharmaceutical, cosmetic, food and agricultural applications. This review in...
122 CitationsSource
#1Silvia Pilco Quesada (State University of Campinas)H-Index: 3
#2Jonas Augusto Rizzato Paschoal (State University of Campinas)H-Index: 15
Last. Felix Guillermo Reyes Reyes (State University of Campinas)H-Index: 24
view all 3 authors...
Aquaculture has become an important source of fish available for human consumption. In order to achieve greater productivity, intensive fish cultivation systems are employed, which can cause greater susceptibility to diseases caused by viruses, bacteria, fungi, and parasites. Antimicrobial substances are compounds used in livestock production with the objectives of inhibiting the growth of microorganisms and treatment or prevention of diseases. It is well recognized that the issues of antimicrob...
52 CitationsSource
#1C. ArulvasuH-Index: 14
A study was conducted to evaluate the efficacy of different dietary doses of Zingiber officinale powder for the immune response and the disease resistance of the Indain major carp (Catla catla) infected by Aeromonas hydrophila. Haematological, biochemical and immunological studies were performed on fish and were analyzed different days of feeding trial. The total erythrocyte, leukocyte count, haemoglobin content and total serum protein were significantly (P<0.05) enhanced in Z. officinale supple...
9 Citations
#2Shyamkumar Rajaram (KSU: King Saud University)H-Index: 2
Last. Shyam Kumar Rajaram (KSU: King Saud University)H-Index: 2
view all 2 authors...
Objective To evaluate the antibacterial properties of Allium sativum (garlic) cloves and Zingiber officinale (ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection.
86 CitationsSource
#1Iram Gull (University of the Punjab)H-Index: 6
#2Mariam Saeed (University of the Punjab)H-Index: 1
Last. Amin M Athar (University of the Punjab)H-Index: 1
view all 6 authors...
Background Herbs and spices are very important and useful as therapeutic agent against many pathological infections. Increasing multidrug resistance of pathogens forces to find alternative compounds for treatment of infectious diseases.
61 CitationsSource
Cited By1
#1Radhakrishnan Palanikani (Manonmaniam Sundaranar University)H-Index: 2
#2Kanagaraj Muthu-Pandian Chanthini (Manonmaniam Sundaranar University)H-Index: 4
Last. A.G. Murugesan (Manonmaniam Sundaranar University)H-Index: 16
view all 7 authors...
Aeromonas hydrophila, an opportunistic fish pathogen, which causes several major diseases including skin ulcer and haemorrhagic septicemia, contributes considerably to the lethality in aquaculture. Chemical and antibiotic treatment employed against A. hydrophila for disease management are expensive and consequently prompted the advent of drug resistance among the pathogens. To overcome these draw backs, alternative aquatic disease control methods using conventional plant-based medicines are focu...
2 CitationsSource