Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study
Abstract
Retrospective studies provide conflicting interpretations of the effect of inherited genetic factors on the prognosis of patients with breast cancer. The primary aim of this study was to determine the effect of a germline BRCA1 or BRCA2 mutation on breast cancer outcomes in patients with young-onset breast cancer.We did a prospective cohort study of female patients recruited from 127 hospitals in the UK aged 40 years or younger at first...
Paper Details
Title
Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study
Published Date
Feb 1, 2018
Journal
Volume
19
Issue
2
Pages
169 - 180
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