Review paper
Nrf2 and AhR in metabolic reprogramming after contaminant exposure
Abstract
Beside their crucial role in xenobiotic biotransformation, AhR and Nrf2 are involved in the regulation of energetic metabolism. Nrf2, as a cytoprotective transcription factor, supply energy for detoxification and antioxidant response. AhR is ligand-activated transcriptional factor implicated in several physiological function. Following pollutant exposure, it acts as a chemosensor to eliminate harmful chemicals. Altogether, AhR and Nrf2 cooperate...
Paper Details
Title
Nrf2 and AhR in metabolic reprogramming after contaminant exposure
Published Date
Apr 1, 2018
Volume
8
Pages
34 - 41
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