Apigenin and luteolin display differential hypocholesterolemic mechanisms in mice fed a high-fat diet

Hypercholesterolemia is a major risk factor in the development of atherosclerosis. High blood cholesterol can be the result of increased biosynthesis or reduced elimination of cholesterol in the system. Increased consumption of fruits and vegetables is recommended for patients suffering from hypercholesterolemia. The plant food flavones apigenin and luteolin have previously been shown to suppress the synthesis of cholesterol in human...