Original paper
S-Glutathionylation of p47phox sustains superoxide generation in activated neutrophils
Volume: 1865, Issue: 2, Pages: 444 - 454
Published: Feb 1, 2018
Abstract
Post-translational modifications (PTMs) induced conformational changes of proteins can cause their activation or inactivation. Neutrophils clear pathogen through phagocytosis and oxidative burst generation, while participate in inflammation through sustained and uncontrolled generation of ROS. In activated PMNs, cytosolic NOX-2 subunit p47phox following phosphorylation interacts with p67phox, p40phox and along with Rac2 translocate to the...
Paper Details
Title
S-Glutathionylation of p47phox sustains superoxide generation in activated neutrophils
Published Date
Feb 1, 2018
Volume
1865
Issue
2
Pages
444 - 454
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Notes
History