Cucurbitacin‐B attenuates CC l4‐induced hepatic fibrosis in mice through inhibition of STAT ‐3
Abstract
Liver fibrosis is a major health concern worldwide. Inhibitors of Signal Transducer and Activator of Transcription 3 ( STAT 3) have been reported to attenuate experimental liver fibrosis. Therefore, the aim of this study was to investigate the potential ameliorative effect of cucurbitacin‐B (Cucu‐B) against CC l 4 ‐induced liver fibrosis in mice. Treatment with Cucu‐B (5 mg/kg) preserved hepatocellular membrane integrity and amended the...
Paper Details
Title
Cucurbitacin‐B attenuates CC l4‐induced hepatic fibrosis in mice through inhibition of STAT ‐3
Published Date
Jan 11, 2018
Volume
91
Issue
4
Pages
933 - 941
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