The role of liver resection in the management of intermediate and advanced stage hepatocellular carcinoma. A systematic review

Background The ideal management for patients with intermediate and advanced stage hepatocellular carcinoma (HCC) is controversial. The main purpose of this systematic review is to examine the role of liver resection in patients with intermediate stage HCC (multinodular HCCs) and in advanced stage HCC [mainly patients with portal vein tumor thrombosis (PVTT)]. Methods A systematic search of the literature was performed in Pud Med and the Cochrane...