Review paper
DNA damage response upon environmental contaminants: An exhausting work for genomic integrity
Abstract
Following exposure to xenobiotics, cellular mechanisms will take place to prevent damages relative to i) DNA, to maintain genome integrity, ii) proteins, to maintain their activities, iii) lipids, to limit peroxidation. This system of cellular defence and resistance is energetically costly. In this commentary review, we discuss the impact of DNA damage and the DNA damage response (DDR) on energetic metabolism. Conversely, we address the question...
Paper Details
Title
DNA damage response upon environmental contaminants: An exhausting work for genomic integrity
Published Date
Apr 1, 2018
Volume
8
Pages
28 - 33
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