The RAS mutation status predicts survival in patients undergoing hepatic resection for colorectal liver metastases: The results from a genetic analysis of all‐RAS

Introduction We investigated the impact of mutations in KRAS exons 3‐4 and NRAS exons 2‐3 in addition to KRAS exon 2, so‐called all‐ RAS mutations, in patients with colorectal liver metastasis (CLM) undergoing hepatic resection. Methods We analyzed 421 samples from CLM patients for their all‐ RAS mutation status to compare the overall survival rate (OS), recurrence‐free survival rate (RFS), and the pattern of recurrence between the patients with...