Excretion of metabolites of the synthetic cannabinoid JWH-018 in urine after controlled inhalation

Each year, synthetic cannabinoids are occurring in high numbers on the illicit drug market but data obtained after controlled application are rare. The present study on pharmacokinetics in urine is part of a pilot study on adverse effects of JWH-018, which is one of the oldest and best known synthetic cannabinoids. Six subjects inhaled smoke from 2 and 3 mg JWH-018. The drug and ten potential metabolites were analyzed in urine samples collected...