S58 Fev1 and feno as predictors of asthma outcomes in children? an individual patient data analysis using data from six feno trials

Introduction

Some guidelines advocate using FEV₁ and/or fractional exhaled nitric oxide (FeNO) in the management of childhood asthma, but evidence supporting these recommendations is generally unsupportive. Our hypothesis was that reduced FEV₁ and/or elevated FeNO measurements were associated with increased risk of future asthma attacks and loss of asthma control.

Methods

Data were obtained from six trials...