Direct Detection of Shigella in Stool Specimens by Use of a Metagenomic Approach
Abstract
The underestimation of Shigella species as a cause of childhood diarrhea disease has become increasingly apparent with quantitative PCR (qPCR)-based diagnostic methods versus culture. We sought to confirm qPCR-based detection of Shigella via a metagenomics approach. Three groups of samples were selected from diarrheal cases from the Global Enteric Multicenter Study: nine Shigella culture-positive and qPCR-positive (culture + qPCR + ) samples,...
Paper Details
Title
Direct Detection of Shigella in Stool Specimens by Use of a Metagenomic Approach
Published Date
Feb 1, 2018
Volume
56
Issue
2
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