Development of fever following first administration of�zoledronate as a prognostic factor in advanced non‑small cell lung cancer patients with bone metastases

Nitrogen‑containing bisphosphonates (N‑BPs), which are usually used for the treatment of advanced cancer with bone metastasis, occasionally cause fever following the first administration. However, it is unclear as to how the development of fever following the first administration of N‑BP is associated with clinical outcome. The aim of the present study was to determine the prognostic value of the development of fever following the first...