Original paper
Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity
Abstract
Tissue-resident macrophages sense the microenvironment and respond by producing signals that act locally to maintain a stable tissue state. It is now known that pancreatic islets contain their own unique resident macrophages, which have been shown to promote proliferation of the insulin-secreting beta cell. However, it is unclear how beta cells communicate with islet-resident macrophages. Here we hypothesised that islet macrophages sense changes...
Paper Details
Title
Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity
Published Date
Sep 7, 2017
Journal
Volume
61
Issue
1
Pages
182 - 192
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Notes
History