Review paper
Towards carborane-functionalised structures for the treatment of brain cancer
Abstract
Boron neutron capture therapy (BNCT) is a promising targeted chemoradiotherapeutic technique for the management of invasive brain tumors, such as glioblastoma multiforme (GBM). A prerequisite for effective BNCT is the selective targeting of tumour cells with 10B-rich therapeutic moieties. To this end, polyhedral boranes, especially carboranes, have received considerable attention because they combine a high boron content with relative low...
Paper Details
Title
Towards carborane-functionalised structures for the treatment of brain cancer
Published Date
Jan 1, 2018
Journal
Volume
23
Issue
1
Pages
63 - 75
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Notes
History