Original paper
Linear polymers of β and γ cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin
Abstract
Cyclodextrins have been used to encapsulate drugs improving their stability and efficiently regulating their release. Polymeric nanoparticles containing cyclodextrins are currently undergoing clinical trials as nanotherapeutics. In this context, we have synthesized new linear polymers based on polyglutamic acid with pendant β- or γ-cyclodextrins, using a high yield reaction route. The new polymers with an average number of about 17 cyclodextrin...
Paper Details
Title
Linear polymers of β and γ cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin
Published Date
Dec 1, 2017
Journal
Volume
177
Pages
355 - 360
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Notes
History