The Chromatin Structure Differentially Impacts High-Specificity CRISPR-Cas9 Nuclease Strategies
Abstract
Genome editing technologies based on RNA-guided nucleases (RGNs) derived from prokaryotic type II CRISPR-Cas9 adaptive immune systems, such as that from Streptococcus pyogenes1Gasiunas G. Barrangou R. Horvath P. Siksnys V. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.Proc. Natl. Acad. Sci. USA. 2012; 109: E2579-E2586Crossref PubMed Scopus (1662) Google Scholar, 2Jinek M. Chylinski K....
Paper Details
Title
The Chromatin Structure Differentially Impacts High-Specificity CRISPR-Cas9 Nuclease Strategies
Published Date
Sep 1, 2017
Volume
8
Pages
558 - 563
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History