Acute physiological and perceptual responses to high-load resistance exercise in hypoxia

Summary This study assessed whether hypoxia during high‐load resistance exercise could enhance the acute physiological responses related to muscular development. Twelve trained men performed exercise in three conditions: normoxia (fraction of inspired oxygen [ F I O 2 ] = 21%), moderate‐level hypoxia ( F I O 2 = 16%) and high‐level hypoxia ( F I O 2 = 13%). Exercise comprised high‐load squats and deadlifts (5 × 5 using 80% of 1‐repetition...