Efficacy and Safety of Spironolactone in Acute Heart Failure

Volume: 2, Issue: 9, Pages: 950 - 950
Published: Sep 1, 2017
Abstract

Importance

Persistent congestion is associated with worse outcomes in acute heart failure (AHF). Mineralocorticoid receptor antagonists administered at high doses may relieve congestion, overcome diuretic resistance, and mitigate the effects of adverse neurohormonal activation in AHF.

Objective

To assess the effect of high-dose spironolactone and usual care on N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels...
Paper Details
Title
Efficacy and Safety of Spironolactone in Acute Heart Failure
Published Date
Sep 1, 2017
Volume
2
Issue
9
Pages
950 - 950
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