Original paper
Efficacy and Safety of Spironolactone in Acute Heart Failure
Abstract
Importance
Persistent congestion is associated with worse outcomes in acute heart failure (AHF). Mineralocorticoid receptor antagonists administered at high doses may relieve congestion, overcome diuretic resistance, and mitigate the effects of adverse neurohormonal activation in AHF.Objective
To assess the effect of high-dose spironolactone and usual care on N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels...Paper Details
Title
Efficacy and Safety of Spironolactone in Acute Heart Failure
Published Date
Sep 1, 2017
Journal
Volume
2
Issue
9
Pages
950 - 950
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Notes
History