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doi.org/10.1038/ncomms16021

Transancestral mapping and genetic load in systemic lupus erythematosus

..., Timothy W. Behrens
78
Nature Communications16.60
Volume: 8, Issue: 1
Published: Jul 17, 2017
Abstract
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparities. We report a large transancestral association study of SLE using Immunochip genotype data from 27,574 individuals of European (EA), African (AA) and Hispanic Amerindian (HA) ancestry. We identify 58 distinct non-HLA regions in EA, 9 in AA and 16 in HA (∼50% of these regions have multiple independent associations); these include 24 novel SLE...
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Paper Details
Title
Transancestral mapping and genetic load in systemic lupus erythematosus
DOI
doi.org/10.1038/ncomms16021
Published Date
Jul 17, 2017
Journal
Nature Communications
Volume
8
Issue
1
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