Evolution of biosynthetic diversity
Abstract
Since the emergence of the last common ancestor from which all extant life evolved, the metabolite repertoire of cells has increased and diversified. Not only has the metabolite cosmos expanded, but the ways in which the same metabolites are made have diversified. Enzymes catalyzing the same reaction have evolved independently from different protein folds; the same protein fold can produce enzymes recognizing different substrates, and enzymes...
Paper Details
Title
Evolution of biosynthetic diversity
Published Date
Jun 27, 2017
Journal
Volume
474
Issue
14
Pages
2277 - 2299
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Notes
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