A multi-tool recipe to identify regions of protein-DNA binding and their influence on associated gene expression

Daniel E. Carlin; Kassi Kosnicki; Sara Garamszegi; Trey Ideker; Helga Thorvaldsdottir; Michael Reich; Jill P. Mesirov

doi:https://doi.org/10.12688/f1000research.11616.2

doi.org/10.12688/f1000research.11616.2

A multi-tool recipe to identify regions of protein-DNA binding and their influence on associated gene expression

,

..., Jill P. Mesirov

Volume: 6, Pages: 784 - 784

Published: Jan 30, 2018

Abstract

One commonly performed bioinformatics task is to infer functional regulation of transcription factors by observing differential expression under a knockout, and integrating DNA binding information of that transcription factor. However, until now, this task has required dedicated bioinformatics support to perform the necessary data integration. GenomeSpace provides a protocol, or “recipe”, and a user interface with inter-operating software...

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Paper Details

Title

A multi-tool recipe to identify regions of protein-DNA binding and their influence on associated gene expression

DOI

doi.org/10.12688/f1000research.11616.2

Published Date

Jan 30, 2018

Journal

F1000Research

Volume

6

Pages

784 - 784

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